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How to Use Nylon Syringe Filters to Remove Particles from Your Samples

A nylon syringe filter is a small disposable filter placed between the syringe and needle to remove particulate matter from liquid samples. Filters are usually made of a porous nylon material that allows fluid to pass while trapping contaminants. The use of syringe filters is common in scientific and medical applications where it is important to remove particles from liquid samples before analysis or injection. For example, syringe filters are often used to purify cells or DNA samples that will be injected into patients. The main purpose of using nylon syringe filters is to improve sample quality by removing unwanted particles. In some cases, filters are also used to protect syringes from possible damage from particles in the sample.

Syringe filters are used to remove particulate contamination from analytical chemical samples before analysis. Filtering the sample before it is injected into the HPLC machine will protect sensitive parts of the instrument from particle buildup and reduce system downtime. For sample filtration, a 0.45 m (HPLC) or 0.2 m (IBM) syringe should be used. Nylon Syringe Filters are used in analytical chemistry including dissolution testing, HPLC/UHPLC, and IP filters. With GxF-configured pre-filters, standard equipment can handle two to four times the amount of particulate matter emitted by syringe filters. The effective filtration area of the PSF syringe filter is much larger than the previous traditional syringe filter, measuring 3.6cm2 which is much larger than 2.8cm2.

These nylon membranes are robust, offer high protein binding, solvent resistance, dimensional stability, and high-temperature resistance as part of their hydrolytic properties, and are backed by inert polyester for sample preparation, biological/buffer sterilization, medical test, and high-temperature applications.

The filter body of the syringe can be made of materials such as polypropylene or nylon. Filter membranes made of PTFE, nylon, or other treated products are an option.

Filters made of nylon have a wide range of properties such as hydrophilicity, flexibility, tear resistance, and autoclavability. Due to their resistance to various organic solvents, they are suitable for samples with high pH values.

Sterile syringe filters are used to decontaminate sterile solutions or to clarify sterile solutions, while non-sterile syringe filters are used to decontaminate general filtration and sample preparation. Syringe filters have two main features: a membrane and a filter housing.